Description

A pyrimidone that is cytosine bearing an N(4)-methyl substituent.

Chemical properties

Chemical formula Net charge Average mass
C5H7N3O 0 125.12860
<i>N</i><sup>4</sup>-methylcytosine

Recommended notation

Name 4-methylcytosine
Abbreviation 4mC

Nomenclature

IUPAC SMILES InChI InChIKey Synonyms
4-(methylamino)pyrimidin-2(1H)-one CNc1cc[nH]c(=O)n1 InChI=1S/C5H7N3O/c1-6-4-2-3-7-5(9)8-4/h2-3H,1H3,(H2,6,7,8,9) PJKKQFAEFWCNAQ-UHFFFAOYSA-N
  • 4-methylamino-1h-pyrimidin-2-one
  • n(4)-methylcytosine

Mapping techniques

Method
Method detail
Resolution
Qualifier
References
SMRT direct detection single-base target sequences
dye-terminator Sanger sequencing direct detection single-base

Nature

Origin Function Functional detail
Organisms
References
natural restriction-modification
  • Bacillus aneurinolyticus
  • Bacillus cenirosporus
  • Bacillus globigii
  • Bacillus stearothermophilus
  • Caldicellulosiruptor kristjanssonii
  • Clostridium thermoaceticum
  • Clostridium thermoautotrophicum
  • Desulfotomaculum nigrificans
  • Geobacillus stearothermophilus
  • Methanococcus thermolithotrophicus
  • Moraxella bovis
  • Proteus vulgaris
  • Rhodopseudomonas sphaeroides
  • Thermobacteroides acetoethylicus
  • Thermus aquaticus
  • Xanthomonas campestris