Description

A nucleoside analogue obtained by formal dehydration across positions 2 and 3 of thymidine. An inhibitor of HIV-1 reverse transcriptase

Chemical properties

Chemical formula Net charge Average mass
C10H12N2O4 0 224.21330
stavudine

Nomenclature

IUPAC SMILES InChI InChIKey Synonyms
1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione Cc1cn([C@@H]2O[C@H](CO)C=C2)c(=O)[nH]c1=O InChI=1S/C10H12N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-4,7-8,13H,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1 XNKLLVCARDGLGL-JGVFFNPUSA-N
  • 1-(2,3-dideoxy-beta-d-glycero-pent-2-enofuranosyl)thymine
  • stv
  • 2',3'-didehydro-3'-deoxythimidine
  • 3'-deoxy-2'-thymidinene
  • sanilvudine
  • estavudina
  • stavudinum
  • d4t